Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893412 | 0.76 | LMNA (0.43) | LMNACYP2A6KDM4EMEN1KMT2A | |
| SCHEMBL2659709 | 0.76 | LMNA (0.43) | LMNACYP2A6KDM4EMEN1KMT2A | |
| SCHEMBL6656755 | 0.76 | CYP1A2 (0.48) | LMNACYP2A6KDM4EMEN1KMT2A | |
| SCHEMBL29984835 | 0.76 | CYP1A2 (0.48) | LMNACYP2A6KDM4EMEN1KMT2A | |
| SCHEMBL2463773 | 0.76 | LMNA (0.43) | LMNACYP2A6KDM4EMEN1KMT2A | |
| SCHEMBL27952899 | 0.76 | LMNA (0.43) | LMNACYP2A6KDM4EMEN1KMT2A | |
| SCHEMBL2917479 | 0.76 | LMNA (0.43) | LMNACYP2A6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5537234 | 0.76 | ALDH1A1 (0.43) | LMNACYP2A6KDM4EMEN1KMT2A | |
| SCHEMBL30332313 | 0.76 | LMNA (0.43) | LMNACYP2A6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4611825 | 0.76 | LMNA (0.43) | LMNACYP2A6KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |