Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177850 | 0.91 | BRAF (0.38) | BRAFLMNA | |
| SCHEMBL13935932 | 0.91 | BRAF (0.51) | BRAF | |
| SCHEMBL4469722 | 0.89 | BRAF (0.42) | BRAFLMNA | |
| SCHEMBL5176153 | 0.89 | MAPK14 (0.40) | BRAFLMNA | |
| SCHEMBL5177405 | 0.88 | BRAF (0.39) | BRAFLMNA | |
| Pivalamide SCHEMBL5177397 | 0.85 | BRAF (0.40) | BRAF | |
| SCHEMBL5179141 | 0.85 | BRAF (0.47) | BRAF | |
| SCHEMBL13935926 | 0.84 | LMNA (0.37) | BRAFLMNA | |
| SCHEMBL4491973 | 0.83 | ABL1 (0.39) | BRAF | |
| SCHEMBL13935944 | 0.83 | BRAF (0.48) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485657-B2 | Anti-cytokine heterocyclic compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-7485657-B2 | Anti-cytokine heterocyclic compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-7485657-B2 | Anti-cytokine heterocyclic compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-02-03 | — | — | US | disclosed |
| EP-1756065-A1 | ANTI-CYTOKINE HETEROCYCLIC COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005115991-A1 | ANTI-CYTOKINE HETEROCYCLIC COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-12-08 | — | — | WO | disclosed |