Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049793 | 0.94 | THRA (0.52) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL11227670 | 0.94 | THRA (0.52) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL449156 | 0.89 | LTB4R (0.44) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL11604986 | 0.89 | THRA (0.50) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL10348761 | 0.87 | THRA (0.56) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL1856295 | 0.86 | THRA (0.40) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL1021215 | 0.86 | THRA (0.44) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL8433693 | 0.86 | THRA (0.58) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL28376630 | 0.86 | THRA (0.58) | THRATHRBALOX5PTGS2PPARA | |
| SCHEMBL29778064 | 0.86 | THRA (0.58) | THRATHRBALOX5PTGS2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065112-A1 | LUBRICANT COMPOSITION WITH IMPROVED VARNISH DEPOSIT RESISTANCE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2012-03-15 | — | — | US | disclosed |