SCHEMBL446440

SCHEMBL446440

CCCc1ccccc1OP(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.43
PPARD Q03181 1/20 0.40
HTR1A P08908 4/20 0.39
ADRA2A P08913 2/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
NISCH Q9Y2I1 1/20 0.39
SLC6A2 P23975 3/20 0.39
SLC6A4 P31645 3/20 0.39
RIPK1 Q13546 1/20 0.39
AR P10275 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
LTB4R Q15722 1/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
ABCB1 P08183 3/20 0.37
DRD2 P14416 2/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
SLC6A3 Q01959 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863853 0.91 HTR1A (0.44) PPARDHTR1AADRA2AADRA2BADRA2C
SCHEMBL1021215 0.90 THRA (0.44) HRH1SLC6A2SLC6A4RIPK1THRA
SCHEMBL11142021 0.87 THRA (0.52) LTB4RLTB4R2THRATHRB
SCHEMBL29813570 0.87 THRA (0.52) LTB4RLTB4R2THRATHRB
SCHEMBL1100666 0.87 THRA (0.52) LTB4RLTB4R2THRATHRB
SCHEMBL9876446 0.87 THRA (0.52) LTB4RLTB4R2THRATHRB
SCHEMBL2019189 0.87 THRA (0.52) LTB4RLTB4R2THRATHRB
SCHEMBL12810345 0.85 L3MBTL1 (0.46) HRH1NISCHSLC6A2SLC6A4RIPK1
SCHEMBL449824 0.85 L3MBTL1 (0.46) HRH1NISCHSLC6A2SLC6A4RIPK1
SCHEMBL1696335 0.79 HRH1 (0.67) HRH1SLC6A2SLC6A4RIPK1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
US-10829708-B2 Composition and method for preventing or reducing engine knock and pre-ignition in high compression spark ignition engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-11-10 US disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
WO-2020139333-A1 FORMULATION APPROACH TO EXTEND THE HIGH TEMPERATURE PERFORMANCE OF LITHIUM COMPLEX GREASES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-07-02 WO disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
US-20200199481-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
EP-2038385-A1 NOVEL BASE STOCK LUBRICANT BLENDS ExxonMobil Research and Engineering Company (US) 2009-03-25 EP disclosed
US-20080207475-A1 High viscosity novel base stock lubricant viscosity blends HAIGH HEATHER M 2008-08-28 US disclosed
US-20080020954-A1 High viscosity novel base stock lubricant extreme viscosity blends HAIGH HEATHER M 2008-01-24 US disclosed
US-20070298990-A1 High viscosity metallocene catalyst pao novel base stock lubricant blends EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-12-27 US disclosed
WO-2007146081-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145923-A1 NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145924-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
US-20070289897-A1 Novel base stock lubricant blends CAREY JAMES T 2007-12-20 US disclosed
US-20020010103-A1 Lubricating oil composition having excellent thermal stability, extreme pressure resistance and anti-wear performance CHEVRON ORONITE JAPAN LIMITED (JP) 2002-01-24 US disclosed
EP-1148114-A2 Lubricating oil compositions having excellent thermal stabilty, extreme pressure resistance and anti-wear performance Chevron Oronite Japan Limited (JP) 2001-10-24 EP disclosed