SCHEMBL8015643

SCHEMBL8015643

CC1(C)CC2(CC(C)(C)c3cc(O)cc(Cl)c32)c2c(Cl)cc(O)cc21

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
FTO Q9C0B1 2/20 0.37
CHRM1 P11229 1/20 0.31
ALOX15 P16050 1/20 0.31
MAOA P21397 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4460425 0.85 CYP3A4 (0.38) CYP3A4HSD17B10HPGDCRHBPCRHR2
SCHEMBL23448752 0.81 PDE7A (0.33) CYP3A4FTO
SCHEMBL4464517 0.78 FTO (0.39) CYP3A4HSD17B10HPGDFTOCHRM1
SCHEMBL8859642 0.73 CYP3A4 (0.34) CYP3A4HSD17B10HPGDCRHBPCRHR2
SCHEMBL4459436 0.73 HNF4A (0.35) CYP3A4FTOCHRM1ALOX15MAOA
SCHEMBL23448751 0.72 RECQL (0.34) HTR2B
SCHEMBL11650120 0.72 CYP3A4 (0.37) CYP3A4HSD17B10HPGDCRHBPCRHR2
SCHEMBL11152989 0.71 ACHE (0.37) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL30773362 0.71 FTO (0.32) FTO
SCHEMBL3256213 0.71 FTO (0.32) FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6080522-A CONTAINING PHOTORESIST AND POLYMER CLARIANT INTERNAITONAL, LTD. (CH) 2000-06-27 US disclosed
EP-0922998-A1 RADIATION-SENSITIVE RESIST COMPOSITION WITH HIGH HEAT RESISTANCE Clariant International Ltd. (CH) 1999-06-16 EP disclosed