Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462915 | 0.90 | ALDH1A1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL1838877 | 0.89 | ALDH1A1 (0.40) | ALDH1A1CYP3A4 | |
| SCHEMBL3768760 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL3781105 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL3775241 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL1840906 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CYP3A4 | |
| SCHEMBL1841634 | 0.66 | ALDH1A1 (0.41) | ALDH1A1CYP3A4 | |
| SCHEMBL5601645 | 0.65 | ALDH1A1 (0.36) | ALDH1A1CYP3A4 | |
| SCHEMBL1841743 | 0.64 | SIGMAR1 (0.42) | ALDH1A1CYP3A4 | |
| SCHEMBL1843106 | 0.62 | ALDH1A1 (0.45) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476663-B2 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-13 | — | — | US | disclosed |
| US-20050277628-A1 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277628-A1 | Substituted thiophene carboxamides | OTC, SLC22A8, DDC | ALDH1A1 910/4885CYP3A4 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.