Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164412 | 0.80 | MAPT (0.36) | MAPTNCEH1NQO1ALDH1A1KDM4E | |
| SCHEMBL9739745 | 0.80 | MAPT (0.40) | MAPTLMNANQO1ALDH1A1KDM4E | |
| SCHEMBL8556354 | 0.79 | MAPT (0.35) | CYP11B1CYP11B2MAPTCYP17A1NQO1 | |
| SCHEMBL4326638 | 0.79 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2MAPTNCEH1 | |
| SCHEMBL8722679 | 0.79 | MAPT (0.35) | MAPTNCEH1NQO1 | |
| SCHEMBL1402281 | 0.77 | IMPDH2 (0.42) | MAPTLMNANQO1 | |
| SCHEMBL8721893 | 0.76 | KMT2A (0.38) | MAPTLMNANCEH1KDM4ESMN1; SMN2 | |
| SCHEMBL5685325 | 0.76 | PDE3B (0.31) | — | |
| SCHEMBL5685068 | 0.75 | CYP2A6 (0.50) | MAPK1 | |
| SCHEMBL28902991 | 0.75 | KDM2B (0.37) | HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641304-B1 | STEREO-SELECTIVE SYNTHESIS OF 2-ARYL-PROPIONIC ACIDS OF HIGH OPTICAL PURITY BY USING CHIRAL OXAZOLINES | CHEMISCH BIOTECHNOLOGISCHE LAB (DE) | 1998-04-08 | — | — | EP | claimed |
| EP-0486045-B1 | S(+)-Phenyl-alkanoic acids and alpha-amino acid containing complexes | PUETTER MEDICE CHEM PHARM (DE) | 1996-05-08 | — | — | EP | claimed |
| EP-0486964-B1 | S(+)-Phenyl-alkanoic acids and alpha-hydroxy-alkanoic acids containing complexes | PUETTER MEDICE CHEM PHARM (DE) | 1996-05-01 | — | — | EP | claimed |
| EP-0486046-B1 | S(+)-Phenyl-alkanoic acids and aminosugar containing complexes | PUETTER MEDICE CHEM PHARM (DE) | 1996-05-01 | — | — | EP | claimed |
| EP-0398288-B1 | Process for preparing optically active 2-arylalkanoic acids, in particular 2-arylpropionic acids | PUETTER MEDICE CHEM PHARM (DE) | 1995-10-18 | — | — | EP | claimed |
| EP-0668259-A1 | A method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1995-08-23 | — | — | EP | claimed |
| US-5434302-A | Method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | PARADIES H HENRICH (DE) | 1995-07-18 | — | — | US | claimed |
| EP-0641304-A1 | STEREO-SELECTIVE SYNTHESIS OF 2-ARYL-PROPIONIC ACIDS OF HIGH OPTICAL PURITY BY USING CHIRAL OXAZOLINES | CHEMISCH BIOTECHNOLOGISCHE LABORATORIEN GMBH (DE) | 1995-03-08 | — | — | EP | claimed |
| US-5380927-A | Process for preparing optically active 2-aryl-alkanoic acids, in particular 2-aryl-propionic acids | MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1995-01-10 | — | — | US | claimed |
| EP-0641304-A4 | STEREO-SELECTIVE SYNTHESIS OF 2-ARYL-PROPIONIC ACIDS OF HIGH OPTICAL PURITY BY USING CHIRAL OXAZOLINES. | KUNICHEM INC (US) | 1994-12-13 | — | — | EP | claimed |
| EP-0486045-A2 | S(+)-Phenyl-alkanoic acids and alpha-amino acid containing complexes | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1992-05-20 | — | — | EP | claimed |
| EP-0486046-A2 | S(+)-Phenyl-alkanoic acids and aminosugar containing complexes | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1992-05-20 | — | — | EP | claimed |
| EP-0398288-A2 | Process for preparing optically active 2-arylalkanoic acids, in particular 2-arylpropionic acids | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1990-11-22 | — | — | EP | claimed |
| EP-0380316-A2 | Preparation of alpha-methylareneacetic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1990-08-01 | — | — | EP | claimed |
| EP-0178580-B1 | INTERMEDIATES FOR THE SYNTHESIS OF CARBOXYLIC ACIDS | ZAMBON S.p.A. (IT) | 1990-01-03 | — | — | EP | claimed |
| US-4888433-A | CHIRAL HALOGENATED KETALS WHICH UNDERGO STEREOSELECTIVE REARRANGEMENT | ZAMBON, S.P.A. (IT) | 1989-12-19 | — | — | US | claimed |
| US-4845243-A | Intermediates and their use in the synthesis of organic compounds | ZAMBON S.P.A. (IT) | 1989-07-04 | — | — | US | claimed |
| EP-0272644-A2 | Intermediates and their use in the synthesis of organic compounds | ZAMBON S.p.A. (IT) | 1988-06-29 | — | — | EP | claimed |
| US-4734507-A | Optically active ketals, processes for their preparation and their use in the synthesis of alpha-arylalkanoic acids | ZAMBON S.P.A. (IT) | 1988-03-29 | — | — | US | claimed |
| EP-0178580-A2 | Intermediates for the synthesis of carboxylic acids | ZAMBON S.p.A. (IT) | 1986-04-23 | — | — | EP | claimed |