Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164412 | 0.80 | MAPT (0.36) | MAPTNQO1NCEH1HPGD | |
| SCHEMBL9739745 | 0.80 | MAPT (0.40) | MAPTNQO1HPGD | |
| SCHEMBL8556354 | 0.79 | MAPT (0.35) | MAPTNQO1 | |
| SCHEMBL4326638 | 0.79 | CYP19A1 (0.41) | MAPTNQO1NCEH1HPGD | |
| SCHEMBL4465114 | 0.79 | CYP19A1 (0.41) | MAPTNQO1NCEH1 | |
| SCHEMBL8721893 | 0.76 | KMT2A (0.38) | MAPTNCEH1 | |
| SCHEMBL28902991 | 0.75 | KDM2B (0.37) | — | |
| SCHEMBL386606 | 0.74 | NQO1 (0.44) | MAPTNQO1HPGD | |
| SCHEMBL8716900 | 0.73 | CA9 (0.48) | MAPTNCEH1HPGD | |
| SCHEMBL8717383 | 0.73 | TDP1 (0.43) | MAPTNCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760055-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | WAKE FOREST UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |