Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 3/20 | 0.33 |
| ▸ | CCND1 | P24385 | 3/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469094 | 0.92 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDTP53MAPT | |
| SCHEMBL3404398 | 0.89 | PDCD1 (0.35) | ALDH1A1HPGDTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL31253552 | 0.89 | PDCD1 (0.35) | ALDH1A1HPGDTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL5609091 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1HPGDMAPTTSHR | |
| Hydrochloric Acid SCHEMBL7943365 | 0.86 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL7592887 | 0.85 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDTP53MAPT | |
| SCHEMBL5678404 | 0.85 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL7983533 | 0.82 | PDCD1 (0.34) | ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL14905713 | 0.82 | NPC1 (0.33) | ALDH1A1HPGDTSHRSMN1; SMN2ENPP3 | |
| SCHEMBL7208808 | 0.81 | ALDH1A1 (0.33) | KDM4EALDH1A1HPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |