SCHEMBL446558

SCHEMBL446558

c1ccc2c(c1)ccc1c(Oc3cccc4c3ccc3ccccc34)cccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.64
ALDH1A1 P00352 3/20 0.55
HSD17B10 Q99714 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP2A6 P11509 1/20 0.55
TSHR P16473 1/20 0.55
PAX8 Q06710 1/20 0.46
CYP1A2 P05177 2/20 0.46
HIF1A Q16665 1/20 0.46
CYP1B1 Q16678 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
MAPT P10636 2/20 0.42
HTR1B P28222 2/20 0.42
GAA P10253 1/20 0.42
RCE1 Q9Y256 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
APEX1 P27695 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441360 0.98 HPRT1 (0.61) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL28188294 0.90 HPRT1 (0.56) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL28393054 0.89 HPRT1 (0.50) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL441525 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL29577853 0.85 HTR1B (0.54) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL442767 0.85 HTR1B (0.54) ALDH1A1HSD17B10TDP1CYP2A6TSHR
Lithium SCHEMBL6571336 0.83 HTR1B (0.52) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL7457103 0.83 HTR1B (0.52) ALDH1A1HSD17B10TDP1CYP2A6TSHR
Methane SCHEMBL10959030 0.83 HTR1B (0.52) ALDH1A1HSD17B10TDP1CYP2A6TSHR
Phosphine SCHEMBL28264511 0.83 HTR1B (0.52) ALDH1A1HSD17B10TDP1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846846-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-30 US claimed
US-20120064725-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-15 US claimed
CN-110447539-B Tissue culture method of bletilla striata seedlings 普安县欣新生物科技有限责任公司 2023-03-28 CN disclosed
CN-115611956-A Preparation method for co-production of bletilla polysaccharide and Militarine, product prepared by preparation method and application of product 云南屈美生物科技有限公司 2023-01-17 CN disclosed
CN-113018388-A Use of anti-allergy composition in preparation of preparation and/or medicament for reducing irritation of azelaic acid 谢志辉生物医药研究院(广州)有限公司 2021-06-25 CN disclosed
CN-107523644-B Identification method of bletilla ochracea 贵州医科大学 2021-01-26 CN disclosed
CN-109574809-B Synthesis method of hydroxyl-substituted phenanthrene derivative 华东理工大学 2020-07-03 CN disclosed
CN-106386054-A Method for under-forest plantation of bletilla striata 湖南苗苗乐生物科技有限公司 2017-02-15 CN disclosed
US-9045587-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
US-20140363768-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-11 US disclosed
US-8846846-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-30 US disclosed
US-20120064725-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-15 US disclosed