SCHEMBL4466255

SCHEMBL4466255

Cc1ccc(NCCO)cc1C

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.76
HTT P42858 2/20 0.59
MAPT P10636 6/20 0.50
POLB P06746 1/20 0.50
SLC2A1 P11166 1/20 0.50
KMT2A Q03164 2/20 0.49
PKM P14618 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49
NPC1 O15118 3/20 0.46
LMNA P02545 3/20 0.46
RAB9A P51151 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 3/20 0.44
GAA P10253 3/20 0.44
KDM4E B2RXH2 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11113125 0.88 ALDH1A1 (0.89) ALDH1A1HTTMAPTPOLBSLC2A1
SCHEMBL4466574 0.84 ALDH1A1 (0.56) ALDH1A1HTTMAPTPOLBSLC2A1
SCHEMBL3266441 0.84 ALDH1A1 (0.61) ALDH1A1HTTMAPTPOLBSLC2A1
SCHEMBL95129 0.84 ALDH1A1 (0.56) ALDH1A1HTTMAPTPOLBSLC2A1
SCHEMBL10476380 0.84 ALDH1A1 (0.56) ALDH1A1HTTMAPTPOLBSLC2A1
SCHEMBL29428385 0.84 ALDH1A1 (0.56) ALDH1A1HTTMAPTPOLBSLC2A1
SCHEMBL13204733 0.83 ALDH1A1 (0.63) ALDH1A1HTTMAPTPOLBKMT2A
SCHEMBL10779665 0.82 ALDH1A1 (0.54) ALDH1A1HTTMAPTPOLBKMT2A
SCHEMBL879890 0.82 ALDH1A1 (0.54) ALDH1A1HTTMAPTPOLBSLC2A1
SCHEMBL850322 0.82 ALDH1A1 (0.54) ALDH1A1HTTMAPTPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118338879-A Curable composition for dental use 可乐丽则武齿科株式会社 2024-07-12 CN disclosed
CN-112545901-B One-part dental adhesive composition 株式会社松风 2024-03-22 CN disclosed
WO-2024043291-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-02-29 WO disclosed
CN-117597099-A Curable composition for dental use 可乐丽则武齿科株式会社 2024-02-23 CN disclosed
CN-112135598-B Macromer-based photocurable dental impression material 登士柏希罗纳有限公司 2023-12-22 CN disclosed
CN-110317226-B Silane coupling compounds and curable dental compositions containing the same 株式会社松风 2023-12-19 CN disclosed
CN-111683640-B dental composition 登士柏希罗纳有限公司 2023-10-27 CN disclosed
CN-114929158-B Method for producing denture, curable composition for photoforming, and kit for producing denture 株式会社德山齿科 2023-10-20 CN disclosed
CN-116916872-A Dental composition 可乐丽则武齿科株式会社 2023-10-20 CN disclosed
CN-113677293-B Curable composition for dental restoration 可乐丽则武齿科株式会社 2023-10-10 CN disclosed
CN-110785159-A Dual paste type dental curable composition 可乐丽则武齿科株式会社 2020-02-11 CN disclosed
CN-106456452-B Self-adhesive dental composite resin 可乐丽则武齿科株式会社 2020-01-31 CN disclosed
EP-3466920-A1 METHOD FOR OBTAINING -AMINO ALCOHOLS Universitat de València (ES) 2019-04-10 EP disclosed
CN-106456452-A Self-adhesive dental composite resin 可乐丽则武齿科株式会社 2017-02-22 CN disclosed
CN-106413667-A Dental adhesive 可乐丽则武齿科株式会社 2017-02-15 CN disclosed
EP-2433940-B9 SPIROIMIDAZOLONE DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2015-10-28 EP disclosed
CN-101600412-B Curable composition for dental use KURARAY MEDICAL INC JP 2012-12-12 CN disclosed
EP-2030998-A1 Method of preparing a transparent moulded article with a thermoplastic polymer and thermosetting polymer alloy base Essilor International (Compagnie Générale D'Optique) (FR) 2009-03-04 EP disclosed
WO-1997002787-A1 FLUORIDE RELEASING DENTAL PIT AND FISSURE SEALANT DISPENSING SYSTEM AND METHOD DENTSPLY INTERNATIONAL INC. (US) 1997-01-30 WO disclosed
US-4223138-A VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE BAYER AKTIENGESELLSCHAFT (DE) 1980-09-16 US disclosed