SCHEMBL4466574

SCHEMBL4466574

Cc1cc(NCCO)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
ESR1 P03372 5/20 0.44
ESR2 Q92731 4/20 0.44
MAPT P10636 3/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTT P42858 2/20 0.43
AR P10275 3/20 0.41
PDE10A Q9Y233 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
MMP14 P50281 1/20 0.39
BLM P54132 1/20 0.39
CASP6 P55212 1/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39
ARG1 P05089 1/20 0.39
SLC2A1 P11166 1/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5809528 0.89 ALDH1A1 (0.67) ALDH1A1ESR1ESR2MAPTTP53
SCHEMBL95129 0.85 ALDH1A1 (0.56) ALDH1A1MAPTHTTMEN1KMT2A
SCHEMBL29428385 0.85 ALDH1A1 (0.56) ALDH1A1MAPTHTTMEN1KMT2A
SCHEMBL4466255 0.84 ALDH1A1 (0.76) ALDH1A1MAPTTP53TDP1HTT
SCHEMBL25856355 0.83 IDO1 (0.46) ALDH1A1ESR1ESR2MAPTTP53
SCHEMBL5547526 0.82 ARG1 (0.57) ALDH1A1MAPTTP53MEN1KMT2A
SCHEMBL18480714 0.81 ALDH1A1 (0.45) ALDH1A1ESR1ESR2MAPTTP53
SCHEMBL11604188 0.81 ALDH1A1 (0.53) ALDH1A1ESR1ESR2MAPTTP53
SCHEMBL10476380 0.81 ALDH1A1 (0.56) ALDH1A1MAPTTDP1HTTAR
SCHEMBL6572164 0.80 ESR1 (0.48) ALDH1A1ESR1ESR2MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
CN-1200682-C Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2005-05-11 CN claimed
EP-1353639-A4 PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR P & G CLAIROL INC (US) 2005-01-26 EP claimed
EP-1353639-A1 PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR Clairol Incorporated (US) 2003-10-22 EP claimed
WO-2002058657-A1 PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR P&G - CLAIROL, INC. (US) 2002-08-01 WO claimed
CN-1278427-A Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2001-01-03 CN claimed
CN-109311879-B Symmetrical/asymmetrical azomethine-type direct dyes comprising at least one pyrazolopyridine unit, method for dyeing 莱雅公司 2023-01-06 CN disclosed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN disclosed
EP-3854376-A2 SYSTEMS FOR CUSTOM COLORATION Coloright Ltd. (IL) 2021-07-28 EP disclosed
CN-107361508-B Custom dyeing system 卡拉莱特有限公司 2020-11-03 CN disclosed
EP-2688549-B1 SYSTEMS FOR CUSTOM COLORATION COLORIGHT LTD (IL) 2020-07-29 EP disclosed
CN-104902865-B Without chemical oxidizing agent, the colouring compositions comprising oxidation dye, alkyl sulfate, alkyl poly glucoside, fatty material and nonionic guar gum 莱雅公司 2019-06-11 CN disclosed
CN-109311879-A Symmetrical (asymmetry) azomethine type direct dyes comprising at least one Pyrazolopyridine unit, the method for using the dyeing keratin fiber 莱雅公司 2019-02-05 CN disclosed
WO-2002017866-A1 PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR P&G-CLAIROL, INC. (US) 2002-03-07 WO disclosed
WO-2002000177-A2 AGENTS CONTAINING A THICKENING SYSTEM, FOR THE OXIDATIVE COLOURING OF KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-01-03 WO disclosed
WO-2001097766-A2 OXIDISED HAIR DYE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed
CN-1278427-A Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2001-01-03 CN disclosed
US-5527509-A QUANTITATIVE ANALYSIS CRANFIELD BIOTECHNOLOGY LTD. (GB) 1996-06-18 US disclosed
EP-0331144-B1 3-SUBSTITUTED PARA-AMINO PHENOLS, PROCESS FOR THEIR PREPARATION, THEIR USE IN DYEING KERATENIC FIBRES AND INTERMEDIATES USED IN THE PREPARATION PROCESS L'OREAL (FR) 1993-06-09 EP disclosed
EP-0331144-A2 3-Substituted para-amino phenols, process for their preparation, their use in dyeing keratenic fibres and intermediates used in the preparation process L'OREAL (FR) 1989-09-06 EP disclosed