Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17215230 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HTTMAPTKDM4ECYP1A2 | |
| SCHEMBL4466255 | 0.82 | ALDH1A1 (0.76) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL4466574 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL10476380 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL12909149 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL16302318 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL850322 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL10779665 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL6342530 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL11018865 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B9 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-10-28 | — | — | EP | disclosed |