Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16289117 | 0.74 | BCHE (0.40) | PDE10AHTTNPC1ALDH1A1RAB9A | |
| SCHEMBL4476804 | 0.74 | SMN1; SMN2 (0.40) | CYP1A2PDE10AHTTNPC1ALDH1A1 | |
| SCHEMBL4365682 | 0.74 | PDE10A (0.38) | CYP1A2PDE10AHTTNPC1ALDH1A1 | |
| SCHEMBL29278047 | 0.74 | PDE10A (0.34) | CYP1A2PDE10AHTTNPC1ALDH1A1 | |
| SCHEMBL5748976 | 0.74 | PDE10A (0.38) | CYP1A2PDE10ANPC1ALDH1A1RAB9A | |
| SCHEMBL4479122 | 0.74 | HTT (0.41) | CYP1A2PDE10AHTTNPC1ALDH1A1 | |
| SCHEMBL294250 | 0.74 | PDE10A (0.34) | CYP1A2PDE10AHTTNPC1ALDH1A1 | |
| SCHEMBL1225371 | 0.72 | MAPT (0.43) | HTTNPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL9871357 | 0.71 | PDE10A (0.40) | CYP1A2PDE10ANPC1ALDH1A1RAB9A | |
| SCHEMBL9870917 | 0.71 | NPC1 (0.39) | PDE10AHTTNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066257-A2 | HETEROCYLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | Sugen, Inc. (US) | 2001-01-10 | — | — | EP | claimed |
| WO-1999048868-A9 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN INC (US) | 2000-04-20 | — | — | WO | claimed |
| WO-1999048868-A2 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN, INC. (US) | 1999-09-30 | — | — | WO | claimed |
| EP-2952096-B1 | Amide compound, an arthropod pest control agent and a method for controlling arthropod pest | SUMITOMO CHEMICAL CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9814235-B2 | Method for controlling arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-14 | — | — | US | disclosed |
| CN-104955332-B | The method of preventing and treating arthropod insect | 住友化学株式会社 | 2017-03-29 | — | — | CN | disclosed |
| EP-2952096-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | Sumitomo Chemical Company, Limited (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-20150344466-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-12-03 | — | — | US | disclosed |
| CN-104955332-A | Method for controlling arthropod pest | SUMITOMO CHEMICAL CO | 2015-09-30 | — | — | CN | disclosed |
| CN-104507927-A | Cyclic azine compound, method for producing same, and organic electroluminescent element containing same | TOSOH CORP | 2015-04-08 | — | — | CN | disclosed |
| US-20150005348-A1 | AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-01-01 | — | — | US | disclosed |
| US-5719275-A | REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC | SANKYO COMPANY, LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5681951-A | REACTING PENICILLIN DERIVATIVE HAVING SULFINYL OR SULFONYL GROUP IN 2 POSITION WITH SUBSTITUTED MERCAPTAN IN PRESENCE OF SALT OF GROUP IIA OR IIIA ELEMENT | SANKYO COMPANY, LIMITED (JP) | 1997-10-28 | — | — | US | disclosed |
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |
| US-5498717-A | CHEMICAL INTERMEDIATES FOR PRODUCING ANTITUMOR POTENTIATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5446164-A | Regioselective cyclization of phenethylamide derivative in presence of phosphoric acid halide, reducing formed compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| CN-1068108-A | Be used to prepare the aza cyclo-butanone derivatives of carbapenem antibiotics | SANKYO CO (JP) | 1993-01-20 | — | — | CN | disclosed |
| EP-0516486-A2 | Azetidinone derivatives useful in the preparation of carbapenem antibiotics | Sankyo Company Limited (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-5051447-A | Applying aromatic oximes to plants, seeds or soils | BASF AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344466-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | H1-0, H1-3, H1-2 | CYP1A2 193/4885PDE10A 2251/4885HTT 1442/4885 |
| US-20150005348-A1 | AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL | RPS8, MT-CO2, ARG1 | CYP1A2 355/4885PDE10A 2449/4885HTT 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.