Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457288 | 0.95 | PLA2G4B (0.52) | KMT2AMEN1NR1H4PLA2G4BMAPT | |
| SCHEMBL4465726 | 0.92 | KMT2A (0.46) | KMT2AMEN1NR1H4MAPTLMNA | |
| SCHEMBL4462759 | 0.89 | PLA2G4B (0.46) | KMT2AMEN1PLA2G4BMAPTLMNA | |
| SCHEMBL4462764 | 0.89 | PLA2G4B (0.46) | KMT2AMEN1PLA2G4BMAPTLMNA | |
| SCHEMBL4460077 | 0.86 | NR4A2 (0.56) | NR1H4 | |
| SCHEMBL4457850 | 0.86 | KMT2A (0.48) | KMT2AMEN1MAPTLMNAHTT | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL4460153 | 0.86 | KDM4E (0.53) | KMT2AMEN1MAPTLMNAHTT | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL4460165 | 0.86 | KDM4E (0.53) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL4461356 | 0.85 | PLA2G4B (0.51) | PLA2G4BMAPTTSHRHSP90AA1KDM4E | |
| SCHEMBL4466851 | 0.83 | MAPT (0.51) | KMT2AMEN1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |