Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL4460153 | 1.00 | KDM4E (0.53) | KDM4EAKR1C3KMT2AFEN1MAPT | |
| SCHEMBL4461928 | 0.90 | FEN1 (0.55) | KDM4EKMT2AFEN1MAPTMEN1 | |
| SCHEMBL4461920 | 0.90 | FEN1 (0.55) | KDM4EKMT2AFEN1MAPTMEN1 | |
| SCHEMBL4460077 | 0.88 | NR4A2 (0.56) | FFAR1GPBAR1CYSLTR1 | |
| SCHEMBL4457850 | 0.88 | KMT2A (0.48) | KDM4EKMT2AMAPTMEN1TDP1 | |
| SCHEMBL4465726 | 0.88 | KMT2A (0.46) | KDM4EKMT2AMAPTMEN1PDE10A | |
| Benzoic Acid SCHEMBL4470207 | 0.87 | ALDH1A1 (0.54) | KDM4EKMT2AMAPTMEN1TDP1 | |
| Benzoic Acid SCHEMBL4470216 | 0.87 | ALDH1A1 (0.54) | KDM4EKMT2AMAPTMEN1TDP1 | |
| SCHEMBL4466848 | 0.86 | KMT2A (0.56) | KDM4EKMT2AMAPTMEN1PDE10A | |
| SCHEMBL4457288 | 0.85 | PLA2G4B (0.52) | KMT2AMAPTMEN1HSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |