Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.44 |
| ▸ | MIF | P14174 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 8/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BACH1 | O14867 | 1/20 | 0.39 |
| ▸ | MAFK | O60675 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15056571 | 0.89 | — | — | |
| SCHEMBL3906746 | 0.75 | NAAA (0.58) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL332767 | 0.75 | NAAA (0.58) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL332468 | 0.75 | NAAA (0.58) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL3906512 | 0.73 | MIF (0.54) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL2141351 | 0.72 | NAAA (0.50) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL330913 | 0.72 | NAAA (0.74) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL7133119 | 0.72 | NAAA (0.74) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL1999782 | 0.72 | NAAA (0.74) | NAAAMIFGSK3BTRPA1KEAP1 | |
| SCHEMBL1233523 | 0.72 | NAAA (0.74) | NAAAMIFGSK3BTRPA1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038937-A1 | TINTED ARTICLE HAVING A HIGH REFRACTIVE INDEX | PPG INDUSTRIES OHIO, INC. (US) | 2009-03-26 | — | — | WO | disclosed |