Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.69 |
| ▸ | SMO | Q99835 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.50 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109094 | 0.87 | HRH3 (0.69) | HRH3SMOOGA | |
| SCHEMBL7535374 | 0.86 | HRH3 (0.55) | HRH3OGA | |
| SCHEMBL1860307 | 0.84 | ALDH1A1 (0.60) | HRH3 | |
| SCHEMBL7530613 | 0.84 | HRH3 (0.54) | HRH3OGA | |
| Potassium Ion SCHEMBL7529500 | 0.84 | HRH3 (0.54) | HRH3OGA | |
| SCHEMBL4460927 | 0.84 | RAB9A (0.56) | HRH3SMOOPRM1OPRK1PARP1 | |
| SCHEMBL12159827 | 0.83 | NPC1 (0.55) | HRH3OGAUBE2T | |
| SCHEMBL14844055 | 0.83 | HRH3 (1.00) | HRH3 | |
| SCHEMBL31061451 | 0.83 | HRH3 (1.00) | HRH3 | |
| SCHEMBL14844995 | 0.83 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141386-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2009-11-26 | — | — | WO | disclosed |