SCHEMBL7535374

SCHEMBL7535374

CC(C)N1CCN(c2ccc(C(=O)Cl)cn2)CC1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 15/20 0.55
OGA O60502 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30109094 0.87 HRH3 (0.69) HRH3OGA
SCHEMBL4467331 0.86 HRH3 (0.69) HRH3OGA
Potassium Ion SCHEMBL7529500 0.84 HRH3 (0.54) HRH3OGA
SCHEMBL7530613 0.84 HRH3 (0.54) HRH3OGA
SCHEMBL1860307 0.84 ALDH1A1 (0.60) HRH3
SCHEMBL30175358 0.82 UBE2T (0.61)
SCHEMBL2772947 0.82 UBE2T (0.61)
SCHEMBL3586636 0.80 HRH3 (0.58) HRH3
SCHEMBL1856613 0.80 KDM4E (0.57) HRH3
SCHEMBL7527367 0.80 KDM4E (0.52) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882716-B1 PYRIDINECARBOXAMIDE DERIVATIVES NISSHIN PHARMA INC (JP) 2002-04-10 EP disclosed
US-6046201-A Pyridinecarboxamide derivatives NISSHIN FLOUR MILLING CO., LTD. (JP) 2000-04-04 US disclosed
EP-0882716-A1 PYRIDINECARBOXAMIDE DERIVATIVES Nisshin Flour Milling Co., Ltd. (JP) 1998-12-09 EP disclosed