Dimethylamine

Dimethylamine

SCHEMBL4467419

CNC.Cc1cc(C)c(O)cc1C

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
KDM4E B2RXH2 2/20 0.57
MAPT P10636 2/20 0.57
CYP3A4 P08684 2/20 0.57
MAPK1 P28482 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
G6PD P11413 1/20 0.57
CYP2C9 P11712 1/20 0.57
PKM P14618 1/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
ALOX12 P18054 1/20 0.57
CYP2C19 P33261 1/20 0.57
CCR6 P51684 1/20 0.57
HIF1A Q16665 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
HSD17B10 Q99714 1/20 0.57
ESR1 P03372 2/20 0.42
ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395019 0.91 KDM4E (0.67) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL70123 0.84 MAPT (0.75) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL6002065 0.81 CYP3A4 (0.50) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL47929 0.81 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTCYP3A4MAPK1
Diethylamine SCHEMBL11661297 0.79 CYP3A4 (0.48) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL1259029 0.78 KDM4E (0.67) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL29600339 0.78 KDM4E (0.67) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL69809 0.77 MAPT (0.56) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL30385731 0.77 MAPT (0.56) ALDH1A1KDM4EMAPTCYP3A4MAPK1
SCHEMBL2741245 0.76 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106634797-A Ultraviolet resistant sealant and preparation method thereof 芜湖县双宝建材有限公司 2017-05-10 CN disclosed
EP-1524289-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-16 EP disclosed
US-20070149639-A1 Polymerizable composition, optical material comprising the composition and method for producing the material HORIKOSHI HIROSHI 2007-06-28 US disclosed
EP-1524289-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-04-20 EP disclosed
US-20040254258-A1 Polymerizable composition, optical material comprising the composition and method for producing the material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2004-12-16 US disclosed
WO-1996005799-A1 HAIR DYE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-02-29 WO disclosed
US-4129555-A IMPROVED IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1978-12-12 US disclosed