SCHEMBL69809

SCHEMBL69809

Cc1cc(O)c(O)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
KDM4E B2RXH2 4/20 0.56
ALDH1A1 P00352 4/20 0.56
CYP3A4 P08684 2/20 0.56
HPGD P15428 2/20 0.56
ALOX15 P16050 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
G6PD P11413 1/20 0.56
CYP2C9 P11712 1/20 0.56
PKM P14618 1/20 0.56
ALOX12 P18054 1/20 0.56
MAPK1 P28482 1/20 0.56
CYP2C19 P33261 1/20 0.56
CCR6 P51684 1/20 0.56
HIF1A Q16665 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
HSD17B10 Q99714 1/20 0.56
GAA P10253 2/20 0.50
TRPA1 O75762 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30385731 1.00 MAPT (0.56) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL30386435 0.96 MAPT (0.53) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL1259029 0.85 KDM4E (0.67) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL29600339 0.85 KDM4E (0.67) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL395019 0.85 KDM4E (0.67) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL70123 0.83 MAPT (0.75) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL6243491 0.82 ALDH1A1 (0.72) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL6346339 0.82 KDM4E (0.48) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL12151750 0.77 MAPT (0.43) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL13090168 0.77 KDM4E (0.43) MAPTKDM4EALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4487975-A Etherification of phenols RHONE-POULENC INDUSTRIES (FR) 1984-12-11 US claimed
US-20230402386-A1 SEMICONDUCTOR DEVICE INCLUDING DIELECTRICS MADE OF POROUS ORGANIC FRAMEWORKS, AND METHOD OF FABRICATING THE SAME TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-12-14 US disclosed
EP-4063954-B1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, POSITIVE PHOTOSENSITIVE DRY FILM, METHOD FOR PRODUCING POSITIVE PHOTOSENSITIVE DRY FILM, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATION FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHINETSU CHEMICAL CO (JP) 2023-10-04 EP disclosed
EP-3398983-B1 POLYMER OF POLYIMIDE PRECURSOR, POSITIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS SHINETSU CHEMICAL CO (JP) 2023-09-27 EP disclosed
EP-4056627-B1 POLYIMIDE-BASED POLYMER, POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE PHOTOSENSITIVE RESIN COMPOSTION, PATTERNING METHOD, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHINETSU CHEMICAL CO (JP) 2023-08-23 EP disclosed
WO-2023109942-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 WO disclosed
WO-2023010282-A1 PROCESS FOR PRODUCTION OF SUBSTITUTED OR UNSUBSTITUTED CATECHOL O, O-DIACETIC ACID ESTERS RHODIA OPERATIONS (FR) 2023-02-09 WO disclosed
WO-2022199677-A1 NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-09-29 WO disclosed
EP-3720835-B1 METHOD FOR PREPARING ETHERS OF CYCLOALIPHATIC OR ARALIPHATIC DIOLS BASF SE (DE) 2022-07-13 EP disclosed
US-11078146-B2 Method for preparing ethers of cycloaliphatic or araliphatic diols BASF SE (DE) 2021-08-03 US disclosed
US-4116929-A POLYESTERS EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-4048140-A 2-HYDROXY-DIPHENYL SULFOXIDE THE B. F. GOODRICH COMPANY (US) 1977-09-13 US disclosed
US-4017508-A POLYMERS EASTMAN KODAK COMPANY (US) 1977-04-12 US disclosed
US-3994926-A Aryl ketals of polycyclic oxo compounds and processes HOFFMANN-LA ROCHE INC. (US) 1976-11-30 US disclosed
US-3972896-A Aryl ketals of polycyclic oxo compounds and processes HOFFMANN-LA ROCHE INC. (US) 1976-08-03 US disclosed
US-3960896-A Aryl ketals of polycyclic oxo compounds and processes HOFFMANN-LA ROCHE INC. (US) 1976-06-01 US disclosed
US-3960895-A Aryl ketals of polycyclic oxo compounds and processes HOFFMANN-LA ROCHE INC. (US) 1976-06-01 US disclosed
US-3950358-A ARYL KETALS OF 3,7-DIHYDROXY-11-OXO-DODEC-1-ENE HOFFMANN-LA ROCHE INC. (US) 1976-04-13 US disclosed
US-3948951-A Aryl ketals of 1-chloro-4-oxo-pentane HOFFMANN-LA ROCHE INC. (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11078146-B2 Method for preparing ethers of cycloaliphatic or araliphatic diols DGKI, MGLL, DEGS1 MAPT 4473/4885KDM4E 3109/4885ALDH1A1 1489/4885
US-20230402386-A1 SEMICONDUCTOR DEVICE INCLUDING DIELECTRICS MADE OF POROUS ORGANIC FRAMEWORKS, AND METHOD OF FABRICATING THE SAME POF1B, PIEZO1, PUF60 MAPT 3688/4885KDM4E 567/4885ALDH1A1 3134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.