N-Acetyl Penicillamine

N-Acetyl Penicillamine

SCHEMBL4468919

CC(=O)N[C@@H](C(=O)O)C(C)(C)S

nearest known ligand 0.43

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
NFKB1 P19838 1/20 0.43
PTGS2 P35354 1/20 0.43
THPO P40225 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 3/20 0.43
PTGS1 P23219 1/20 0.43
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Acetyl Penicillamine SCHEMBL34351 1.00 MAPT (0.43) MAPTKDM4ETHRBALOX15NFKB1
N-Acetyl Penicillamine SCHEMBL521764 1.00 MAPT (0.43) MAPTKDM4ETHRBALOX15NFKB1
N-Acetyl Penicillamine SCHEMBL15106832 0.92 ALDH1A1 (0.41) MAPTKDM4ETHRBALOX15NFKB1
N-Acetyl Penicillamine SCHEMBL8398514 0.85 ALDH1A1 (0.39) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL1236539 0.81 CA2 (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL8415890 0.81 CA2 (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL2515799 0.81 CA2 (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL929561 0.80 MAPT (0.58) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL3680194 0.80 MAPT (0.37) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL21816921 0.80 ALDH1A1 (0.41) MAPTKDM4EALDH1A1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250109377-A1 CELL CULTURE METHODS UNIV MASSACHUSETTS (US) 2025-04-03 US claimed
US-20250079000-A1 METHODS AND MARKERS FOR DIAGNOSIS OF PARKINSON'S DISEASE BERG SURVIVOR’S TRUST 2025-03-06 US claimed
EP-4479519-A2 CELL CULTURE METHODS The University of Massachusetts (US) 2024-12-25 EP claimed
CN-119013413-A Cell culture method 马萨诸塞大学 2024-11-22 CN claimed
US-12104106-B2 Compositions of chiral molecules and perovskite nanocrystals and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2024-10-01 US claimed
WO-2024151479-A1 CONTAINERS AND METHODS FOR NITRIC OXIDE STERILIZATION STERILE STATE, LLC (US) 2024-07-18 WO claimed
CN-117715664-A Creation of cell-adhesive 3D printed objects using functionalized and non-functionalized ECM, ECM fragments, peptides and bioactive components 朗格生物技术公共公益股份有限公司 2024-03-15 CN claimed
EP-4333917-A1 USE OF FUNCTIONALIZED AND NON-FUNCTIONALIZED ECMS, ECM FRAGMENTS, PEPTIDES AND BIOACTIVE COMPONENTS TO CREATE CELL ADHESIVE 3D PRINTED OBJECTS Lung Biotechnology PBC (US) 2024-03-13 EP claimed
CN-117401836-A Method for efficiently reducing polycyclic aromatic hydrocarbon pollutants by using biological Fenton and activated sludge coupling system and application of method 中国石油化工股份有限公司 2024-01-16 CN claimed
WO-2023154910-A9 CELL CULTURE METHODS THE UNIVERSITY OF MASSACHUSETTS (US) 2023-12-07 WO claimed
US-9371226-B2 Methods for forming particles BATTELLE ENERGY ALLIANCE, LLC (US) 2016-06-21 US claimed
US-9212349-B2 Method to produce virus in cultured cells THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-12-15 US claimed
EP-2606351-B1 IN-SITU REAGENT FOR DETECTION OF PROTEINS QUEEN MARY & WESTFIELD COLLEGE (GB) 2015-05-06 EP claimed
US-20140113353-A1 Method to Produce Virus in Cultured Cells THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2014-04-24 US claimed
EP-2699672-A1 METHOD TO PRODUCE VIRUS IN CULTURED CELLS The Trustees of Princeton University (US) 2014-02-26 EP claimed
WO-2013158706-A1 METHOD TO PRODUCE VIRUS IN CULTURED CELLS SUPPLEMENTED WITH ALPHA-KETOGLUTARATE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2013-10-24 WO claimed
WO-2012145375-A1 METHOD TO PRODUCE VIRUS IN CULTURED CELLS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-10-26 WO claimed
WO-2009151744-A1 S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES GALLEON PHARMACEUTICALS, INC. (US) 2009-12-17 WO claimed
US-20070243132-A1 Transdermal delivery of pharmaceutical agents APOLLO LIFE SCIENCES LIMITED (AU) 2007-10-18 US claimed
EP-0165274-B1 UTILIZATION OF CYSTEIN DERIVATIVES OR THE SALTS THEREOF TO ENHANCE INSULIN SECRETION OF THE ISLETS OF LANGERHANS OF THE PANCREAS AMMON, Hermann P.T. (DE) 1989-03-01 EP claimed