N-Acetyl Penicillamine

N-Acetyl Penicillamine

SCHEMBL521764

CC(=O)NC(C(=O)O)C(C)(C)S

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
NFKB1 P19838 1/20 0.43
PTGS2 P35354 1/20 0.43
THPO P40225 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 3/20 0.43
PTGS1 P23219 1/20 0.43
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Acetyl Penicillamine SCHEMBL34351 1.00 MAPT (0.43) MAPTKDM4ETHRBALOX15NFKB1
N-Acetyl Penicillamine SCHEMBL4468919 1.00 MAPT (0.43) MAPTKDM4ETHRBALOX15NFKB1
N-Acetyl Penicillamine SCHEMBL15106832 0.92 ALDH1A1 (0.41) MAPTKDM4ETHRBALOX15NFKB1
N-Acetyl Penicillamine SCHEMBL8398514 0.85 ALDH1A1 (0.39) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL1236539 0.81 CA2 (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL8415890 0.81 CA2 (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL2515799 0.81 CA2 (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL929561 0.80 MAPT (0.58) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL3680194 0.80 MAPT (0.37) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL21816921 0.80 ALDH1A1 (0.41) MAPTKDM4EALDH1A1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 578 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070151-A Nitric oxide generating/releasing medical device 斯特里莱国家有限公司 2026-05-19 CN claimed
US-12605332-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2026-04-21 US claimed
US-20250281531-A1 METHODS AND COMPOSITIONS FOR DETOXIFICATION OF CHRONIC EXPOSURE TO TOXINS MDLifespan Enterprises, LLC 2025-09-11 US claimed
WO-2025078955-A1 WATER-BASED NITRIC OXIDE GENERATING/RELEASING MATERIALS STERILE STATE, LLC (US) 2025-04-17 WO claimed
WO-2025078956-A1 NITRIC OXIDE GENERATING/RELEASING MEDICAL DEVICES STERILE STATE, LLC (US) 2025-04-17 WO claimed
EP-4337197-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL CONDITIONS Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2024-03-20 EP claimed
WO-2023081681-A1 NITRIC OXIDE DONORS FOR USE IN SURGICAL RECOVERY BAXTER INTERNATIONAL INC. (US) 2023-05-11 WO claimed
EP-4161598-A1 DEVICE FOR PROVIDING THERAPEUTIC GAS Biocrede Inc. (US) 2023-04-12 EP claimed
CN-113876950-B Microneedle patch suitable for NO-synergetic photodynamic therapy and preparation method thereof 浙江大学 2023-02-10 CN claimed
WO-2022187702-A1 PREVENTION AND TREATMENT OF CORONAVIRUS AND RELATED RESPIRATORY INFECTIONS PHILERA NEW ZEALAND (NZ) 2022-09-09 WO claimed
EP-1324974-A2 DRUGS FOR DIABETES Nicox S.A. (FR) 2003-07-09 EP claimed
WO-2003013499-A2 DRUGS FOR VASCULOPATIES NICOX S.A. (FR) 2003-02-20 WO claimed
WO-2003000642-A2 DRUGS FOR CHRONIC PAINS NICOX S.A. (FR) 2003-01-03 WO claimed
WO-2002100400-A1 ORGANIC NITRATE-BASED COMPOUNDS FOR THE TREATMENT OF VASCULOPATHIES NICOX S.A. (FR) 2002-12-19 WO claimed
WO-2002092072-A2 DRUGS FOR THE TREATMENT OF THE ALZHEIMER DISEASE NICOX S.A. (FR) 2002-11-21 WO claimed
CN-1354740-A Pharmaceutical compounds NICOX SA (FR) 2002-06-19 CN claimed
WO-2002030867-A2 DRUGS FOR DIABETES NICOX S.A. (FR) 2002-04-18 WO claimed
EP-1169030-A1 AGENTS AND METHODS FOR PROMOTING PRODUCTION GAINS IN ANIMALS The Horticulture and Food Research Institute of New Zealand Limited (NZ) 2002-01-09 EP claimed
WO-2000054766-A1 AGENTS AND METHODS FOR PROMOTING PRODUCTION GAINS IN ANIMALS THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 2000-09-21 WO claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605332-B2 Transdermal delivery formulations NOS1, NOS2, VDR MAPT 1646/4885KDM4E 2777/4885THRB 877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.