Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28970307 | 0.78 | TERT (0.53) | FAAHCYP1A2CYP2C19KMT2ATERT | |
| SCHEMBL9118984 | 0.78 | TERT (0.48) | SOAT1FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL30713063 | 0.77 | FAAH (0.46) | SOAT1FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL9807728 | 0.77 | FAAH (0.46) | SOAT1FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL9807731 | 0.77 | FAAH (0.46) | SOAT1FAAHCYP1A2CYP2C19KMT2A | |
| Ammonia Solution, Strong SCHEMBL30713068 | 0.75 | FAAH (0.45) | SOAT1FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL9788737 | 0.75 | DNM1 (0.46) | FAAHCYP1A2CYP2C19MAPTBLM | |
| SCHEMBL22558363 | 0.74 | TERT (0.58) | FAAHCYP1A2CYP2C19KMT2ATERT | |
| SCHEMBL19093967 | 0.74 | CNR1 (0.47) | FAAHCYP1A2CYP2C19MAPTBLM | |
| SCHEMBL10939149 | 0.73 | TERT (0.52) | SOAT1FAAHCYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1714977-B1 | Synthesis of cyclosporin analogs | ISOTECHNIKA INC (CA) | 2009-03-11 | — | — | EP | claimed |
| EP-1714977-A2 | Synthesis of cyclosporin analogs | Isotechnika Inc. (CA) | 2006-10-25 | — | — | EP | claimed |
| EP-1436321-A2 | SYNTHESIS OF CYCLOSPORIN ANALOGS | Isotechnika Inc. (CA) | 2004-07-14 | — | — | EP | claimed |
| US-20030212249-A1 | Synthesis of cyclosporin analogs | ISOTECHNIKA, INC. (CA) | 2003-11-13 | — | — | US | claimed |
| WO-2003033526-A2 | SYNTHESIS OF CYCLOSPORIN ANALOGS | ISOTECHNIKA INC. (CA) | 2003-04-24 | — | — | WO | claimed |
| EP-1714977-B1 | Synthesis of cyclosporin analogs | ISOTECHNIKA INC (CA) | 2009-03-11 | — | — | EP | disclosed |
| EP-1714977-A2 | Synthesis of cyclosporin analogs | Isotechnika Inc. (CA) | 2006-10-25 | — | — | EP | disclosed |