Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.48 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.48 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.48 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.48 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.48 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.48 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.48 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295495 | 1.00 | CTBP2 (0.49) | CTBP2PLA2G10PLA2G2AFFAR1PLA2G1B | |
| SCHEMBL8257100 | 0.89 | TBXAS1 (0.53) | PLA2G10PLA2G2AFFAR1PLA2G1BPLA2G5 | |
| SCHEMBL24899382 | 0.86 | MAOB (0.45) | CTBP2MEN1MAPTKMT2ACTSB | |
| SCHEMBL9631293 | 0.86 | MAOB (0.45) | CTBP2MEN1MAPTKMT2ACTSB | |
| SCHEMBL7440986 | 0.85 | CTBP2 (0.51) | CTBP2MEN1MAPTKMT2APPARG | |
| SCHEMBL24915424 | 0.84 | POLB (0.47) | CTBP2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL7381207 | 0.84 | CYP1A2 (0.62) | CTBP2PPARGPPARA | |
| SCHEMBL30963031 | 0.83 | MEN1 (0.50) | CTBP2MEN1MAPTKMT2APOLB | |
| SCHEMBL17929000 | 0.83 | MEN1 (0.50) | CTBP2MEN1MAPTKMT2APOLB | |
| SCHEMBL15093693 | 0.83 | MEN1 (0.50) | CTBP2MEN1MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815935-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |
| EP-2065360-B1 | Use of 3-methylbenzyl isobutyrate as a fragrance compound | SYMRISE AG (DE) | 2013-06-19 | — | — | EP | disclosed |
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-25 | — | — | US | disclosed |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |
| EP-1747186-B1 | Fragrant composition comprising 3-methylbenzyl-isobutyrat | SYMRISE GMBH & CO KG (DE) | 2009-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | CTBP2 1088/4885PLA2G10 571/4885PLA2G2A 684/4885 |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | CTBP2 1088/4885PLA2G10 571/4885PLA2G2A 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.