Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469435 | 0.84 | CTBP2 (0.49) | POLBCTBP2KDM4EHSD17B10MEN1 | |
| SCHEMBL9631293 | 0.84 | MAOB (0.45) | POLBTAAR1IDO1CTBP2HSD17B10 | |
| SCHEMBL19295495 | 0.84 | CTBP2 (0.49) | POLBCTBP2KDM4EHSD17B10MEN1 | |
| SCHEMBL24899382 | 0.84 | MAOB (0.45) | POLBTAAR1IDO1CTBP2HSD17B10 | |
| SCHEMBL14431748 | 0.83 | NOS3 (0.51) | POLBTAAR1PARP1IDO1 | |
| SCHEMBL934633 | 0.83 | GRIA2 (0.49) | TAAR1PARP1CTBP2KDM4EMAPT | |
| SCHEMBL14432430 | 0.83 | NOS3 (0.51) | POLBTAAR1PARP1IDO1 | |
| SCHEMBL14016346 | 0.83 | POLB (0.47) | POLBTAAR1PARP1IDO1CTBP2 | |
| SCHEMBL28662062 | 0.83 | ADRB2 (0.45) | ALDH1A1PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL14672775 | 0.82 | EPHX1 (0.46) | POLBNR3C2KMT2AMAPK8CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102507-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |