Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455601 | 1.00 | FDPS (0.46) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL4455593 | 1.00 | FDPS (0.46) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL4456240 | 0.79 | NR3C1 (0.41) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL4466714 | 0.79 | NR3C1 (0.41) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL10299127 | 0.78 | HSPA5 (0.49) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL13124663 | 0.76 | HSPA5 (0.47) | FDPSNR3C1NPC1HSPA5MEN1 | |
| SCHEMBL43586 | 0.76 | FDPS (0.53) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL43587 | 0.76 | FDPS (0.53) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL288965 | 0.76 | FDPS (0.53) | FDPSNR3C1HTTNPC1HSPA5 | |
| SCHEMBL4453124 | 0.72 | FDPS (0.49) | FDPSNR3C1HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |