Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954393 | 0.87 | GPR35 (0.58) | GPR35THRBALDH1A1TDP1KCNMA1 | |
| SCHEMBL29589123 | 0.85 | GPR35 (0.60) | GPR35ALDH1A1TDP1KCNMA1TSHR | |
| SCHEMBL71886 | 0.85 | GPR35 (0.60) | GPR35ALDH1A1TDP1KCNMA1TSHR | |
| SCHEMBL28745129 | 0.83 | GPR35 (0.58) | GPR35ALDH1A1TDP1KCNMA1TSHR | |
| SCHEMBL4734285 | 0.83 | TSHR (0.56) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL2572950 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL206164 | 0.81 | TSHR (0.58) | GPR35ALDH1A1KCNMA1TSHRMEN1 | |
| SCHEMBL11765678 | 0.81 | GPR35 (0.51) | GPR35ALDH1A1TDP1KCNMA1TSHR | |
| SCHEMBL30662861 | 0.81 | TSHR (0.58) | GPR35ALDH1A1KCNMA1TSHRMEN1 | |
| SCHEMBL16959347 | 0.81 | GPR35 (0.51) | GPR35ALDH1A1TDP1KCNMA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6157579-A | — | — | None | — | — | JP | disclosed |
| US-20090143426-A1 | Synthesis of 1,3,6-trisubstituted-2-carboxyquinol-4-ones as selective ET A antagonists and their use as medicaments | STEPHANI RALPH ANTHONY | 2009-06-04 | — | — | US | disclosed |
| US-7364881-B1 | Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2008-04-29 | — | — | US | disclosed |
| JP-H06157579-A | NEW GLYCOSIDE AND UV ABSORBING AND SCATTERING AGENT CONTAINING THE SAME | SATO TAKESHI | 1994-06-03 | — | — | JP | disclosed |