SCHEMBL4470199

SCHEMBL4470199

CC1C(C)(C)c2cc(Cl)c(O)cc2C12CC(C)(C)c1cc(Cl)c(O)cc12

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.43
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11158693 0.80 FTO (0.56) FTOHPGDTSHRHSD17B10HTR2C
SCHEMBL4457787 0.76 HSP90AA1 (0.35)
SCHEMBL4460410 0.75 FTO (0.51) FTOHPGDTSHRHSD17B10
SCHEMBL8014576 0.75 FTO (0.51) FTOHPGDTSHRHSD17B10
SCHEMBL11157334 0.69 FTO (0.46) FTOHPGDTSHRHSD17B10
SCHEMBL11165344 0.67 FTO (0.43) FTOTSHR
SCHEMBL11141905 0.67 FTO (0.43) FTOTSHRHSD17B10
SCHEMBL16812205 0.66 FTO (0.42) FTOTSHRHTR2C
SCHEMBL6027262 0.65 FTO (0.44) FTOHPGDTSHRHSD17B10
SCHEMBL9327955 0.64 FTO (0.61) FTOHPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed