Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460410 | 1.00 | FTO (0.51) | FTOTSHRHSD17B10HPGDRXRA | |
| SCHEMBL11158693 | 0.90 | FTO (0.56) | FTOTSHRHSD17B10HPGDRXRA | |
| SCHEMBL29569404 | 0.86 | RXRA (0.35) | FTOHSD17B10HPGDRXRARARB | |
| SCHEMBL196263 | 0.86 | RXRA (0.35) | FTOHSD17B10HPGDRXRARARB | |
| SCHEMBL30062005 | 0.78 | ALDH1A1 (0.37) | FTOHSD17B10HPGDRXRARARB | |
| SCHEMBL218400 | 0.78 | ALDH1A1 (0.37) | FTOHSD17B10HPGDRXRARARB | |
| SCHEMBL11157334 | 0.78 | FTO (0.46) | FTOTSHRHSD17B10HPGDRXRA | |
| SCHEMBL4460568 | 0.77 | RARG (0.35) | FTORXRARARBRARG | |
| SCHEMBL14945765 | 0.77 | ALDH1A1 (0.36) | FTOHSD17B10RXRAALDH1A1CYP3A4 | |
| SCHEMBL12190600 | 0.77 | KDM4E (0.35) | FTOHSD17B10HPGDRXRARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080833-A | BIS(HYDROXYALKOXYLATED) 1,1'-SPIROBIINDAN POLYCARBONATES AND POLYESTERS POLYMERS AND CURABLE COMPOUNDS SUCH AS BIS(ACRYLATED ALKOXY)SPIROBIINDANS; ALSO POLYAMIDES AND POLYIMIDES CONTAINING SPIROBIINDAN GROUPS | MITSUI CHEMICALS, INC. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0822545-A2 | Optical component and spirobiindan polymer therefor | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1998-02-04 | — | — | EP | disclosed |