Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 5/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460410 | 0.90 | FTO (0.51) | FTOTSHRHSD17B10HPGDRXRA | |
| SCHEMBL8014576 | 0.90 | FTO (0.51) | FTOTSHRHSD17B10HPGDRXRA | |
| SCHEMBL16812205 | 0.84 | FTO (0.42) | FTOTSHRRXRARARBRARG | |
| SCHEMBL11157334 | 0.82 | FTO (0.46) | FTOTSHRHSD17B10HPGDRXRA | |
| SCHEMBL4470199 | 0.80 | FTO (0.43) | FTOTSHRHSD17B10HPGDHTR2C | |
| SCHEMBL11141905 | 0.80 | FTO (0.43) | FTOTSHRHSD17B10RXRACA1 | |
| SCHEMBL11165344 | 0.80 | FTO (0.43) | FTOTSHRRXRAALDH1A1TDP1 | |
| SCHEMBL6027262 | 0.77 | FTO (0.44) | FTOTSHRHSD17B10HPGDRXRA | |
| SCHEMBL11137776 | 0.77 | RXRA (0.39) | FTOHSD17B10HPGDRXRARARB | |
| SCHEMBL9327955 | 0.76 | FTO (0.61) | FTOTSHRHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370505-A | 1,1,3,3-Substituted hydroxyindanes | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-25 | — | — | US | disclosed |
| US-3954889-A | Process for the production of 1,1,3,3-substituted hydroxyindanes | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |