SCHEMBL447060

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10940020	0.84	CYP19A1 (0.56)	CYP19A1HSP90AA1HSP90AB1IDO1KMO
	SCHEMBL31452201	0.83	MAPT (0.43)	GAACYP2A6ALDH1A1CYP1A2CYP3A4
	SCHEMBL5786593	0.83	MAPT (0.43)	GAACYP2A6ALDH1A1CYP1A2CYP3A4
	SCHEMBL28845264	0.82	IDO1 (0.49)	CYP19A1IDO1KMOGRM5L3MBTL1
	SCHEMBL10939917	0.81	CYP19A1 (0.45)	CYP19A1HSP90AA1HSP90AB1IDO1KMO
	SCHEMBL31380425	0.81	ALDH1A1 (0.43)	HSP90AA1HSP90AB1IDO1L3MBTL1GAA
	SCHEMBL31011602	0.81	CYP19A1 (0.45)	CYP19A1IDO1KMOGAAALDH1A1
	SCHEMBL2350242	0.81	NPC1 (0.47)	IDO1KMOL3MBTL1TDP1NPC1
	SCHEMBL1914955	0.81	HSP90AA1 (0.59)	CYP19A1HSP90AA1HSP90AB1KMOL3MBTL1
	SCHEMBL29002136	0.81	HSP90AA1 (0.46)	CYP19A1HSP90AA1HSP90AB1IDO1KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.