Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18936186 | 0.93 | PTPN1 (0.55) | PTPN1ALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL16439916 | 0.93 | PTPN1 (0.55) | PTPN1ALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL449111 | 0.85 | PTPN1 (0.45) | PTPN1ALDH1A1ALOX15CASP1CASP7 | |
| SCHEMBL9804973 | 0.82 | PTPN1 (0.52) | PTPN1ALDH1A1CYP3A4ALOX15CASP1 | |
| SCHEMBL28256745 | 0.81 | PTPN1 (0.52) | PTPN1ALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL14189031 | 0.79 | PTPN1 (0.46) | PTPN1ALDH1A1CYP3A4ALOX15CASP1 | |
| SCHEMBL7534910 | 0.77 | TSHR (0.46) | PTPN1ALDH1A1CYP3A4ALOX15CASP1 | |
| SCHEMBL12310184 | 0.76 | PTPN1 (0.35) | PTPN1ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL29728142 | 0.76 | PTPN1 (0.55) | PTPN1ALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL28017002 | 0.76 | PTPN1 (0.55) | PTPN1ALDH1A1CYP3A4HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120061620-A1 | Fluorinated Silyethynyl Pentacene Compounds and Compositions and Methods of Making and Using the Same | 3M INNOVATIVE PROPERTIES COMPANY | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061620-A1 | Fluorinated Silyethynyl Pentacene Compounds and Compositions and Methods of Making and Using the Same | PFAS, FLNB, FLNA | PTPN1 4062/4885ALDH1A1 1699/4885CYP3A4 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.