Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447064 | 0.85 | PTPN1 (0.48) | PTPN1ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL18936186 | 0.83 | PTPN1 (0.55) | PTPN1ALDH1A1ALOX12HSD17B10KIF11 | |
| SCHEMBL16439916 | 0.83 | PTPN1 (0.55) | PTPN1ALDH1A1ALOX12HSD17B10KIF11 | |
| SCHEMBL9243671 | 0.75 | NPC1 (0.55) | PTPN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL10057987 | 0.74 | MEN1 (0.50) | NPC1RAB9AALDH1A1PLA2G1BL3MBTL1 | |
| SCHEMBL54876 | 0.74 | MEN1 (0.50) | NPC1RAB9AALDH1A1PLA2G1BL3MBTL1 | |
| SCHEMBL2516264 | 0.74 | MEN1 (0.50) | NPC1RAB9AALDH1A1PLA2G1BL3MBTL1 | |
| SCHEMBL30130196 | 0.74 | MEN1 (0.56) | NPC1RAB9AALDH1A1PLA2G1BL3MBTL1 | |
| SCHEMBL354514 | 0.74 | MEN1 (0.56) | NPC1RAB9AALDH1A1PLA2G1BL3MBTL1 | |
| SCHEMBL29364188 | 0.74 | MEN1 (0.56) | NPC1RAB9AALDH1A1PLA2G1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435446-B1 | FLUORINATED SILYLETHYNYL PENTACENE COMPOUNDS AND COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2016-11-30 | — | — | EP | disclosed |
| US-8920679-B2 | Fluorinated silylethynyl pentacene compounds and compositions and methods of making and using the same | 3M INNOVATIVE PROPERTIES CO. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120061620-A1 | Fluorinated Silyethynyl Pentacene Compounds and Compositions and Methods of Making and Using the Same | 3M INNOVATIVE PROPERTIES COMPANY | 2012-03-15 | — | — | US | disclosed |
| WO-2010138807-A1 | FLUORINATED SILYLETHYNYL PENTACENE COMPOUNDS AND COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061620-A1 | Fluorinated Silyethynyl Pentacene Compounds and Compositions and Methods of Making and Using the Same | PFAS, FLNB, FLNA | PTPN1 4062/4885NPC1 674/4885RAB9A 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.