Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462749 | 0.87 | RCE1 (0.55) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| Benzoic Acid SCHEMBL4470216 | 0.87 | ALDH1A1 (0.54) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| Benzoic Acid SCHEMBL4470207 | 0.87 | ALDH1A1 (0.54) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| SCHEMBL4461259 | 0.87 | ALDH1A1 (0.52) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| SCHEMBL4465726 | 0.84 | KMT2A (0.46) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL4460165 | 0.84 | KDM4E (0.53) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| SCHEMBL4458854 | 0.84 | GSTP1 (0.52) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| SCHEMBL4458860 | 0.84 | GSTP1 (0.52) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL4460153 | 0.84 | KDM4E (0.53) | KMT2APDE10AMAPTKDM4EALDH1A1 | |
| SCHEMBL4466848 | 0.83 | KMT2A (0.56) | KMT2APDE10AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |