SCHEMBL4470742

SCHEMBL4470742

COc1c(O[Si](C)(C)C)cc(C)c(O[Si](C)(C)C)c1OC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP19A1 P11511 4/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NQO2 P16083 2/20 0.32
KCNA3 P22001 1/20 0.31
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1243920 0.73 ACHE (0.56) ACHEALDH1A1CYP19A1NQO2CYP3A4
SCHEMBL30835564 0.73 ACHE (0.56) ACHEALDH1A1CYP19A1NQO2CYP3A4
SCHEMBL12758265 0.73 NQO2 (0.32) NQO2MAPT
SCHEMBL10459836 0.68 ALDH1A1 (0.35) ACHEALDH1A1CYP19A1KDM4EHPGD
SCHEMBL8254929 0.67 ACHE (0.46) ACHEALDH1A1CYP19A1KDM4ENQO2
SCHEMBL16433700 0.66
SCHEMBL7778455 0.66 NQO2 (0.34) ALDH1A1KDM4EL3MBTL1NQO2
SCHEMBL9638274 0.66
SCHEMBL11707401 0.65 ACHE (0.46) ACHEALDH1A1CYP19A1NQO2CYP3A4
SCHEMBL22660986 0.65 KDM4E (0.49) ALDH1A1KDM4EHPGDCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915333-B1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSM IP ASSETS BV (NL) 2015-06-03 EP disclosed
US-7601877-B2 Condensation of a prenol or isoprenol with a hydroquinone or derivative in the presence of 0.005-1.0 mol percent of a Bronsted or Lewis acid catalyst selected from a bismuth, indium or Group 3 chloride, a heteropolyacid, and an NH- or a CH-acidic compound, oxidizing the ubihydroquinone; improved kinetics DSM IP ASSETS B.V. (NL) 2009-10-13 US disclosed
US-20080275275-A1 Process for the Preparation of Ubihydroquinones and Ubiquinones DSM IPASSETS B.V. (NL) 2008-11-06 US disclosed
EP-1915333-A1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSMIP Assets B.V. (NL) 2008-04-30 EP disclosed
WO-2007017168-A1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSM IP ASSETS B.V. (NL) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275275-A1 Process for the Preparation of Ubihydroquinones and Ubiquinones UBE2D3, UBE2L3, UBE2I ACHE 2233/4885ALDH1A1 813/4885CYP19A1 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.