Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216449 | 0.89 | ALDH1A1 (0.60) | ALDH1A1HPGDFDPSSLC47A1SMN1; SMN2 | |
| SCHEMBL1413128 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDFDPS | |
| SCHEMBL146980 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPSSLC47A1ADRA1D | |
| SCHEMBL1270863 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPSSLC47A1 | |
| SCHEMBL18135161 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPSSLC47A1ADRA1D | |
| SCHEMBL146981 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPS | |
| SCHEMBL12199241 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPSSLC47A1ADRA1D | |
| SCHEMBL11497625 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPSSLC47A1 | |
| SCHEMBL4748034 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPSSLC47A1ADRA1D | |
| SCHEMBL30775394 | 0.70 | ALDH1A1 (0.71) | ALDH1A1HPGDFDPSSLC47A1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582771-B2 | Process for the synthesis of cPLA2 inhibitors | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050049296-A1 | Process for the synthesis of cPLA2 inhibitors | WYETH (US) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049296-A1 | Process for the synthesis of cPLA2 inhibitors | PLA2G12A, ACOX3, CPA2 | ALDH1A1 1353/4885HPGD 709/4885FDPS 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.