Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4467823 | 0.76 | HTR6 (0.32) | HTR6HTR2ASIGMAR1KDM1ARCOR1 | |
| SCHEMBL11034547 | 0.68 | HTR6 (0.33) | HTR6HTR2ASIGMAR1KDM1ARCOR1 | |
| SCHEMBL27874174 | 0.66 | HTR2A (0.33) | HTR6HTR2ASIGMAR1KDM1A | |
| Hydrochloric Acid SCHEMBL7822194 | 0.64 | HTR6 (0.33) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL27487479 | 0.64 | HTR6 (0.31) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL8623411 | 0.64 | BRD4 (0.32) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL22116258 | 0.62 | HTR6 (0.33) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL22116218 | 0.62 | HTR6 (0.33) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL22116215 | 0.62 | HTR6 (0.33) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL30441536 | 0.62 | HTR6 (0.33) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1671983-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 2006-06-21 | — | — | EP | claimed |
| EP-1671983-B1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA SA (ES) | 2009-02-25 | — | — | EP | disclosed |
| EP-1671983-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 2006-06-21 | — | — | EP | disclosed |