SCHEMBL4471577

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2169310	0.85	P2RX7 (0.67)	P2RX7ABCB11HIF1APOLBNPC1
	SCHEMBL4465535	0.82	P2RX7 (0.69)	P2RX7ABCB11HIF1A
	SCHEMBL4482089	0.80	P2RX7 (1.00)	P2RX7ABCB11HIF1A
	SCHEMBL4465210	0.80	P2RX7 (0.72)	P2RX7ABCB11HIF1APOLBNPC1
	SCHEMBL2168393	0.78	P2RX7 (1.00)	P2RX7ABCB11HIF1A
	SCHEMBL5118090	0.78	P2RX7 (0.67)	P2RX7ABCB11HIF1APOLBNPC1
	SCHEMBL4472433	0.78	P2RX7 (0.72)	P2RX7ABCB11HIF1APOLBTP53
	SCHEMBL4463754	0.77	P2RX7 (0.62)	P2RX7ABCB11HIF1APOLBTP53
	SCHEMBL4458899	0.77	P2RX7 (0.62)	P2RX7ABCB11HIF1APOLBNPC1
	SCHEMBL5111555	0.76	P2RX7 (0.66)	P2RX7ABCB11HIF1APOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.