SCHEMBL4472433

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2168393	0.82	P2RX7 (1.00)	P2RX7HIF1AABCB11KMT2A
	SCHEMBL4471577	0.78	P2RX7 (0.69)	P2RX7HIF1AABCB11TP53POLB
	SCHEMBL4482089	0.77	P2RX7 (1.00)	P2RX7HIF1AABCB11
	SCHEMBL4465210	0.77	P2RX7 (0.72)	P2RX7HIF1AABCB11TP53KDM4E
	SCHEMBL14609832	0.76	P2RX7 (0.71)	P2RX7HIF1AABCB11KDM4EMEN1
	SCHEMBL14009830	0.76	SMN1; SMN2 (0.62)	HIF1ATP53MEN1ALDH1A1MAPT
	SCHEMBL2169310	0.76	P2RX7 (0.67)	P2RX7HIF1AABCB11TP53KDM4E
	SCHEMBL5118090	0.76	P2RX7 (0.67)	P2RX7HIF1AABCB11POLBMAPT
	SCHEMBL4465535	0.75	P2RX7 (0.69)	P2RX7HIF1AABCB11
	SCHEMBL5111555	0.74	P2RX7 (0.66)	P2RX7HIF1AABCB11TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.