SCHEMBL4471795

SCHEMBL4471795

Oc1ccc(C(c2ccc(O)c(F)c2)c2ccc(O)c(F)c2)cc1F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.55
CYP17A1 P05093 1/20 0.41
ESR1 P03372 4/20 0.41
ESR2 Q92731 4/20 0.41
HSD17B1 P14061 3/20 0.41
HSD17B2 P37059 3/20 0.41
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GRIN2B Q13224 1/20 0.38
CA3 P07451 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
MGLL Q99685 3/20 0.37
SNCA P37840 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRA2A P08913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1596219 0.98 SHBG (0.53) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL25121951 0.91 SHBG (0.49) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL835607 0.91 SHBG (0.49) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL29948072 0.91 SHBG (0.49) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL27620448 0.89 SHBG (0.47) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL29948191 0.89 SHBG (0.47) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL833877 0.89 SHBG (0.47) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL30343458 0.85 SHBG (0.55) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL1597362 0.85 SHBG (0.55) SHBGCYP17A1ESR1ESR2HSD17B1
SCHEMBL31375413 0.84 SHBG (0.47) SHBGCYP17A1ESR1ESR2HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6288204-B1 CONDENSATION POLYMERIZATION OF BISPHENOL A, TRIHYDRIC PHENOL, AND PHOSGENE; ADDING TETRAAMMONIUM SALT AND MONOHYDRIC PHENOL FOR MOLECULAR WEIGHT CONTROL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-09-11 US disclosed