SCHEMBL4471814

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4458525	0.85	KDM4E (0.58)	P2RX7ABL1GAARECQLKDM4E
	SCHEMBL5350275	0.77	RAB9A (0.68)	NPC1GAAKDM4EMAPTPOLB
	SCHEMBL17476093	0.77	PFKFB3 (0.58)	NPC1GAARECQLGFERKDM4E
	SCHEMBL1765095	0.77	MAPT (0.60)	ABL1NPC1GAARECQLGFER
	SCHEMBL16414810	0.76	NPC1 (0.50)	P2RX7ABL1NPC1GAARECQL
	SCHEMBL14806771	0.75	EIF4E (0.68)	EIF4E
	SCHEMBL14797271	0.75	EIF4E (0.59)	NPC1KDM4ERAB9AMEN1KMT2A
	SCHEMBL4462430	0.75	P2RX7 (0.56)	P2RX7NPC1GAAKDM4EMAPT
	SCHEMBL27972612	0.74	EIF4E (0.64)	NPC1KDM4ERAB9AMEN1KMT2A
	SCHEMBL19626555	0.73	MAPT (0.69)	NPC1GAARECQLGFERKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.