SCHEMBL4458525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4471814	0.85	P2RX7 (0.57)	KDM4EPOLBGAAHTTRAB9A
	SCHEMBL1765095	0.80	MAPT (0.60)	KDM4EPOLBGAARAB9AALDH1A1
	SCHEMBL17336686	0.78	KDM4E (0.52)	KDM4EPOLBGAAHTTRAB9A
	SCHEMBL17336947	0.78	EIF4E (0.71)	KDM4ERAB9AEIF4E
	SCHEMBL19627004	0.76	ABL1 (0.59)	KDM4EPOLBGAAHTTRAB9A
	SCHEMBL4094288	0.76	RECQL (0.58)	KDM4EPOLBGAAHTTRAB9A
	SCHEMBL16995078	0.75	SORT1 (0.49)	P2RX7EIF4EALDH1A1
	SCHEMBL3346275	0.75	KDM4E (0.55)	KDM4EPOLBGAAHTTRAB9A
	SCHEMBL599260	0.75	RAB9A (0.97)	KDM4EPOLBGAAHTTRAB9A
	SCHEMBL601034	0.75	HTT (0.68)	KDM4EPOLBGAAHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.