Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638364 | 0.75 | HTR2C (0.59) | HTR2CHTR6EPHX2 | |
| SCHEMBL3289559 | 0.75 | DRD2 (0.60) | HTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL6643702 | 0.74 | HTR2C (0.57) | HTR2CHTR6EPHX2 | |
| SCHEMBL13116668 | 0.73 | HTR2C (0.56) | HTR2CEPHX2 | |
| SCHEMBL1030418 | 0.71 | HTR2C (0.58) | HTR2C | |
| Hydrochloric Acid SCHEMBL31195199 | 0.71 | HTR2C (0.44) | HTR2CEPHX2 | |
| SCHEMBL1537940 | 0.71 | DRD2 (0.55) | HTR2CHTR6 | |
| SCHEMBL10495676 | 0.70 | HTR2C (0.68) | HTR2CEPHX2 | |
| SCHEMBL3680133 | 0.70 | HTR2C (0.67) | HTR2CEPHX2 | |
| SCHEMBL1127150 | 0.69 | HTR2C (0.53) | HTR2CHTR6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538113-B2 | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-26 | — | — | US | claimed |
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | claimed |
| US-7538113-B2 | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-26 | — | — | US | disclosed |
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | GNRHR, LHCGR, FSHR | HTR2C 277/4885KCNH2 339/4885HTR6 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.