Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840086 | 1.00 | POLB (0.48) | POLBRECQLESR2KAT8PPARA | |
| SCHEMBL6839192 | 0.98 | POLB (0.49) | POLBRECQLESR2KAT8PPARA | |
| SCHEMBL4601026 | 0.94 | POLB (0.50) | POLBRECQLESR2CYP3A4KDM4E | |
| SCHEMBL11960981 | 0.88 | KAT8 (0.47) | KAT8PPARAESR1ADRA2AADORA3 | |
| SCHEMBL6839421 | 0.87 | POLB (0.52) | POLBRECQLESR2CYP3A4LMNA | |
| SCHEMBL11718596 | 0.86 | KAT8 (0.46) | KAT8PPARAESR1ADRA2AADORA3 | |
| SCHEMBL9139426 | 0.84 | KAT8 (0.47) | KAT8PPARAESR1ADRA2AADORA3 | |
| SCHEMBL16341724 | 0.84 | KAT8 (0.47) | KAT8PPARAESR1ADRA2AADORA3 | |
| SCHEMBL29405900 | 0.84 | KAT8 (0.47) | KAT8PPARAESR1ADRA2AADORA3 | |
| SCHEMBL8369675 | 0.84 | KAT8 (0.57) | KAT8PPARAESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065181-A1 | METHOD OF PROVIDING NEUROPROTECTION USING SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY | 2012-03-15 | — | — | US | disclosed |
| WO-2010138633-A1 | METHOD OF PROVIDING NEUROPROTECTION USING SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 2010-12-02 | — | — | WO | disclosed |
| US-20040116618-A1 | Polycarbonate resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1384755-A1 | POLYCARBONATE RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065181-A1 | METHOD OF PROVIDING NEUROPROTECTION USING SUBSTITUTED PORPHYRINS | SOD1, PYGB, PSAP | POLB 3145/4885RECQL 2178/4885ESR2 3909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.