Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783798 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL4472454 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL4460262 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL13783924 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL4460265 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL4462424 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMAPTTRPV1 | |
| SCHEMBL13784016 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMAPTTRPV1 | |
| SCHEMBL4462419 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMAPTTRPV1 | |
| SCHEMBL4774278 | 0.81 | POLB (0.38) | ALDH1A1MAPTGAATRPV1MEN1 | |
| SCHEMBL4779535 | 0.79 | TRPV1 (0.43) | ALDH1A1GAATRPV1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |