Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 4/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783924 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL4460262 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL4472460 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13783798 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL4472454 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL4451601 | 0.81 | CASP3 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CASP3 | |
| SCHEMBL13783979 | 0.81 | CASP3 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CASP3 | |
| SCHEMBL4451608 | 0.81 | CASP3 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CASP3 | |
| SCHEMBL4774278 | 0.79 | POLB (0.38) | ALDH1A1GAAPOLBMEN1KMT2A | |
| SCHEMBL4455115 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |