Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783798 | 0.79 | ALDH1A1 (0.46) | TRPV1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL4472454 | 0.79 | ALDH1A1 (0.46) | TRPV1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL4472460 | 0.79 | ALDH1A1 (0.46) | TRPV1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL4774278 | 0.77 | POLB (0.38) | TRPV1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL4458301 | 0.77 | TRPV1 (0.61) | TRPV1NPC1RAB9A | |
| SCHEMBL4458303 | 0.77 | TRPV1 (0.61) | TRPV1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4780345 | 0.76 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL13783924 | 0.76 | ALDH1A1 (0.44) | TRPV1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL4460262 | 0.76 | ALDH1A1 (0.44) | TRPV1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL4460265 | 0.76 | ALDH1A1 (0.44) | TRPV1MEN1ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |