SCHEMBL4473036

SCHEMBL4473036

Cc1cc(-c2ccccc2)c(C)c(-c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.48
SQOR Q9Y6N5 1/20 0.47
BACE1 P56817 1/20 0.46
NUDT1 P36639 1/20 0.46
ESR2 Q92731 1/20 0.45
PSMB5 P28074 2/20 0.44
HDAC7 Q8WUI4 1/20 0.44
PTGS1 P23219 1/20 0.44
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 2/20 0.43
ALOX12 P18054 1/20 0.43
ACHE P22303 1/20 0.43
CYP2A6 P11509 1/20 0.43
CYP2B6 P20813 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9423370 0.88 PSMB5 (0.49) METAP2SQORBACE1NUDT1ESR2
Water SCHEMBL19349803 0.86 PSMB5 (0.47) METAP2SQORBACE1NUDT1ESR2
SCHEMBL15856382 0.85 METAP2 (0.46) METAP2SQORBACE1NUDT1ESR2
SCHEMBL28220857 0.84 MAOB (0.49) METAP2SQORBACE1NUDT1ESR2
SCHEMBL29473772 0.84 CYP2A6 (0.46) METAP2SQORBACE1NUDT1ESR2
SCHEMBL28598819 0.84 CYP2A6 (0.46) METAP2SQORBACE1NUDT1ESR2
SCHEMBL20663065 0.84 PTGS1 (0.58) SQORBACE1ESR2PTGS1PDCD1
SCHEMBL27781809 0.82 METAP2 (0.47) METAP2BACE1NUDT1ESR2PSMB5
SCHEMBL29473767 0.81 SQOR (0.50) METAP2SQORBACE1NUDT1LMNA
SCHEMBL27407938 0.81 METAP2 (0.40) METAP2SQORBACE1NUDT1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787827-B2 Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions DONGGUAN STEPHEN CATALYST CO., LTD. (CN) 2023-10-17 US disclosed
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 US disclosed
WO-2019170163-A1 TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS 东莞市均成高新材料有限公司 2019-09-12 WO disclosed
EP-1498432-B1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN CO (JP) 2009-09-02 EP disclosed
US-20050159566-A1 improved flexibility, and transparency, heat sealability and hot tackiness; good softness, a less stickiness, and an good compatibility with polyolefin resins; for sanitary materials, packing, bookbinding, fibers IDEMITSU KOSAN CO., LTD (JP) 2005-07-21 US disclosed
EP-1498432-A1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 2005-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787827-B2 Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions WEE1, WEE2, NOTUM METAP2 1797/4885SQOR 554/4885BACE1 1326/4885
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, LIN28A, OR51E2 METAP2 3974/4885SQOR 3176/4885BACE1 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.