SCHEMBL4473312

SCHEMBL4473312

CC(C)(C)OC(=O)NCC=CCN

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
PTPN11 Q06124 1/20 0.38
CTSK P43235 2/20 0.38
CA1 P00915 6/20 0.38
CA2 P00918 6/20 0.38
CA12 O43570 4/20 0.36
CA9 Q16790 4/20 0.36
EPHX1 P07099 1/20 0.36
CA7 P43166 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8260176 1.00 TDP1 (0.43) TDP1MAOAMAOBMEN1GAA
SCHEMBL4473309 1.00 TDP1 (0.43) TDP1MAOAMAOBMEN1GAA
Hydrochloric Acid SCHEMBL22121480 0.98 TDP1 (0.42) TDP1MAOAMAOBMEN1GAA
Hydrochloric Acid SCHEMBL21616394 0.98 TDP1 (0.42) TDP1MAOAMAOBMEN1GAA
SCHEMBL18262010 0.90 TDP1 (0.50) TDP1MAOAMAOBMEN1GAA
SCHEMBL18262007 0.90 TDP1 (0.50) TDP1MAOAMAOBMEN1GAA
SCHEMBL18487257 0.90 TDP1 (0.50) TDP1MAOAMAOBMEN1GAA
SCHEMBL17302431 0.86 TDP1 (0.41) TDP1MAOAMAOBMEN1GAA
SCHEMBL23992116 0.84 TDP1 (0.30) TDP1
SCHEMBL661593 0.83 TDP1 (0.49) TDP1MAOAMAOBMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920172-B Interferon-stimulated protein targeted compound, radioactive marker thereof, and preparation methods and applications of interferon-stimulated protein targeted compound and radioactive marker 厦门大学 2022-03-22 CN claimed
CN-112920172-A Interferon-stimulated protein targeted compound, radioactive marker thereof, and preparation methods and applications of interferon-stimulated protein targeted compound and radioactive marker 厦门大学 2021-06-08 CN claimed
EP-3919488-B1 IMMUNOMODULATOR HITGEN INC (CN) 2025-08-27 EP disclosed
WO-2024200838-A1 NEW ODILORHABDINS ANALOGUES AS ANTIBIOTICS AGAINST MULTI-RESISTANT BACTERIA NOSOPHARM (FR) 2024-10-03 WO disclosed
WO-2024174863-A1 STING AGONIST AND PREPARATION METHOD AND MEDICAL USE THEREOF 深圳众格生物科技有限公司 2024-08-29 WO disclosed
US-20240269305-A1 STING AGONIST SUITABLE AS PAYLOAD OF ANTIBODY DRUG CONJUGATE HITGEN INC (CN) 2024-08-15 US disclosed
CN-112300227-B Heterocyclic amide compound, and preparation method and application thereof 江西济民可信集团有限公司 2023-11-28 CN disclosed
CN-114174285-B Heterocyclic amide compound, and preparation method and application thereof 上海济煜医药科技有限公司 2023-10-31 CN disclosed
CN-116829551-A Immunomodulatory antibody drug conjugates 思进公司 2023-09-29 CN disclosed
CN-111417630-B Modulators of interferon gene stimulating factor (STING) 葛兰素史克知识产权开发有限公司 2023-06-06 CN disclosed
CN-113444023-B Synthesis method and application of tert-butoxycarbonyl protected ammonia compound 成都先导药物开发股份有限公司 2023-05-02 CN disclosed
CN-111499617-A Immunomodulator 成都先导药物开发股份有限公司 2020-08-07 CN disclosed
WO-2020156363-A1 IMMUNOMODULATOR 成都先导药物开发股份有限公司 2020-08-06 WO disclosed
CN-111417630-A Modulators of interferon gene stimulating factor (STING) 葛兰素史克知识产权开发有限公司 2020-07-14 CN disclosed
CN-111194214-A Methods of administering STING agonists 葛兰素史密斯克莱知识产权发展有限公司 2020-05-22 CN disclosed
US-7511077-B2 Diamine calcium channel blockers NEUROMED PHARMACEUTICALS LTD. (CA) 2009-03-31 US disclosed
EP-1846365-A1 DIAMINE CALCIUM CHANNEL BLOCKERS Neuromed Pharmaceuticals, Ltd. (CA) 2007-10-24 EP disclosed
WO-2006084369-A9 DIAMINE CALCIUM CHANNEL BLOCKERS NEUROMED PHARMACEUTICALS LTD (CA) 2007-01-11 WO disclosed
US-20060235050-A1 Diamine calcium channel blockers NUEROMED TECHNOLOGIES, INC. (CA) 2006-10-19 US disclosed
WO-2006084369-A1 DIAMINE CALCIUM CHANNEL BLOCKERS NEUROMED PHARMACEUTICALS LTD. (CA) 2006-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235050-A1 Diamine calcium channel blockers CACNA1G, CACNA1H, CACNA1I TDP1 1412/4885MAOA 834/4885MAOB 535/4885
US-20240269305-A1 STING AGONIST SUITABLE AS PAYLOAD OF ANTIBODY DRUG CONJUGATE STING1, TBK1, CGAS TDP1 588/4885MAOA 2139/4885MAOB 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.